RESULTS: The donor selection is the first and only step to reduce the risk of TTPIs in endemic and non endemic areas of Iran. ...CONCLUSIONS: Since malaria, toxoplasmosis and VL are endemic in parts of Iran, as well as the increasing travels to endemic areas and immigrations from endemic to non endemic areas of parasitic infections, the extensive use of blood and blood components and the asymptomatic occurrence of most parasitic infections in blood donors, the donor selection strategy is not sufficient to prevent the TTPIs. ...