The most common AEs were hypercholesterolemia 18 cases , increased triglycerides 17 cases , increased transaminases 15 cases , rash 14 cases , neutropenia 7 cases , digestive disorders 3 cases and respiratory disorders 3 cases . ...A non TNF biological agent like tocilizumab with or without methotrexate is recommended in those patients. In this study, tocilizumab treatment improved the number of responders, the number of patients in remission, and the evolution of disease activity. ...