To test this hypothesis, we used a mouse model in which F1 generation animals were exposed prenatally to an endocrine disruptor, di 2 ethylhexyl phthalate DEHP , and the severity of impacted reproductive traits was compared between the F3 generation males that were descendants of F1 males paternal lineage and those from F1 females maternal lineage . ...Paternal lineage F3 DEHP males exhibited decreased fertility, testicular steroidogenic capacity, and spermatogenesis that were more severely impaired than those of maternal lineage males. ...