Human coronavirus and several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. ...We compared the antiviral activity of Morus spp. on enveloped and nonenveloped viral pathogens, such as human coronavirus HCoV 229E and different members of the Picornaviridae family human poliovirus 1, human parechovirus 1 and 3, and human echovirus 11. ...