Related Articles Key criteria for the ethical acceptability of COVID 19 human challenge studies Report of a WHO Working Group Vaccine 2020 Oct 28 Authors Jamrozik E Littler K Bull S Emerson C Kang G Kapulu M Rey E Saenz C Shah S Smith PG Upshur R Weijer C Selgelid MJ WHO Working Group for Guidance on Human Challenge Studies in COVID 19 Abstract This report of the WHO Working Group for Guidance on Human Challenge Studies in COVID 19 outlines ethical standards for COVID 19 challenge studies It includes eight Key Criteria related to scientific justification risk benefit assessment consultation and engagement co ordination of research site selection participant selection expert review and informed consent The document aims to provide comprehensive guidance to scientists research ethics committees funders policymakers and regulators in deliberations regarding SARS CoV 2 challenge studies by outlining criteria that would need to be satisfied in order for such studies to be ethically acceptable PMID 33341309 PubMed as supplied by publisher