DESIGN, SETTING, AND PARTICIPANTS: Similar to prior conferences, experts identified 10 important areas of controversy regarding the management of advanced prostate cancer: locally advanced disease, biochemical recurrence after local therapy, treating the primary tumour in the metastatic setting, metastatic hormone sensitive na ve prostate cancer, nonmetastatic castration resistant prostate cancer, metastatic castration resistant prostate cancer, bone health and bone metastases, molecular characterisation of tissue and blood, inter and intrapatient heterogeneity, and adverse effects of hormonal therapy and their management. ...The conference, which has been held three times since 2015, aims to share the knowledge of world experts in prostate cancer management with health care providers worldwide. ...