The present study investigates the potential neuroprotective effect of Argan Oil AO , a natural vegetable oil, commonly used in folk Moroccan medicines, on adolescent intermittent ethanol intoxications IEI induced voluntary ethanol consumption and withdrawal syndrome in rats. ...We found that AO pre treatment decreased significantly the voluntary ethanol consumption induced by adolescent IEI. Also, by establishing a low ethanol consumption, AO pre treatment counteracts negative effects of ethanol withdrawal and anxiety like behaviors in ethanol treated rats after 72 h of abstinence. ...