Related Articles Impact of repurposed drugs on the symptomatic COVID 19 patients J Infect Public Health 2020 Dec 07 14 1 24 38 Authors Hussain I Hussain A Alajmi MF Rehman MT Amir S Abstract An outbreak of severe acute respiratory syndrome coronavirus 2 SARS CoV 2 a novel coronavirus capable of causing coronavirus disease 2019 COVID 19 was declared as a global public health emergency on January 30 2020 by the World Health Organization In this devastating situation precautionary measures early diagnosis and repurposed drugs appear to be timely and decisive factors by which to handle this problem until the discovery of an effective dedicated vaccine or medicine is made Currently some researchers and clinicians have claimed evidence exists in favor of the use of some antimalarial drugs chloroquine hydroxychloroquine antiviral drugs remdesivir favipiravir lopinavir ritonavir umifenovir vitamins traditional Chinese medicines and herbal medicines against SARS CoV 2 infection Based on the available literature this review article sought to highlight the current understanding of the origin transmission diagnosis precautionary measures infection and drug action mechanisms therapeutic role and toxicities of targeted drugs for the prevention and cure of COVID 19 This review may be useful for developing further strategies as a blueprint and understanding the mentioned drugs mechanisms to elucidate the possible target of action by which to successfully freeze the replication of the SARS CoV 2 virus PMID 33341481 PubMed as supplied by publisher