Related Articles Gastrointestinal Bleeding in Hospitalized COVID 19 Patients A Propensity Score Matched Cohort Study J Intern Med 2020 Dec 20 Authors Trindade AJ Izard S Coppa K Hirsch JS Lee C Satapathy SK Northwell COVID 19 Research Consortium Abstract BACKGROUND AND AIMS Gastrointestinal GI bleeding has been observed among patients hospitalized with COVID 19 Recently anticoagulation has shown to decrease mortality but it is unclear if this contributes to increased GI bleeding The aims of this study are 1 to examine if there are risk factors for GI bleeding in COVID 19 patients 2 to study whether there is a mortality difference between hospitalized patients with COVID 19 with and without GI bleeding METHODS This is a propensity score matched case control study from a large health system in the New York metropolitan area between March 1st and April 27th COVID 19 patients with GI bleeding were matched 1 1 to COVID 19 patients without bleeding using a propensity score that took into account comorbidities demographics GI bleeding risk factors and length of stay RESULTS Of 11 158 hospitalized with COVID 19 314 patients were identified with GI bleeding The point prevalence of GI bleeding was 3 There were no identifiable risk factors for GI bleeding Use of anticoagulation medication or antiplatelet agents were not associated with increased risk of GI bleeding in COVID 19 patients For patients that developed a GI bleed during the hospitalization there was an increased mortality risk in the GI bleeding group OR 1 58 p 0 02 CONCLUSION Use of anticoagulation or antiplatelet agents were not risk factors for GI bleeding in a large cohort of hospitalized COVID 19 patients Those with GI bleeding during the hospitalization had increased mortality PMID 33341978 PubMed as supplied by publisher