METHODS: A total of 159 TI patients in Sulaymaniyah province, northeastern Iraq. TI patients in Sulaymaniyah province, northeastern Iraq. ...Among disease related morbidities documented, bone disease amounted to 53 facial deformity and osteoporosis , followed by endocrinopathies 17.6 growth retardation and subclinical hypothyroidism , cholelithiasis 13.8 , pulmonary hypertension 11.3 , and abnormal liver function test 7.5 , whereas venous thrombosis, extramedullary hemopoiesis, and leg ulcer were less frequently observed. ...