Antibody based therapies are a promising treatment option for managing ebolavirus infections. Several Ebola virus EBOV specific and, more recently, pan ebolavirus antibody cocktails have been described. Here, we report the development and assessment of a Sudan virus SUDV specific antibody cocktail. We produced a panel of SUDV glycoprotein GP specific human chimeric monoclonal antibodies mAbs using both plant and mammalian expression systems and completed head to head in vitro and in vivo evaluations. ...