In this project, we are trying to review the articles that discuss the relationship between insulin signaling and Alzheimer's disease AD . ...We used Pubmed database to collect our data and used the following keywords: Alzheimer's disease, insulin signaling pathway, type 3 diabetes, type 2 diabetes, insulin, and insulin resistance in our revision we included free articles that were published in the last 10 years and excluded articles that were written in any language other than English. ...