Related Articles Stroke as a Neurological Complication of COVID 19 A Systematic Review and Meta Analysis of Incidence Outcomes and Predictors J Stroke Cerebrovasc Dis 2020 Dec 15 30 3 105549 Authors Siow I Lee KS Zhang JJY Saffari SE Ng A Young B Abstract INTRODUCTION COVID 19 is a multi system infection which predominantly affects the respiratory system but also causes systemic inflammation endothelialitis and thrombosis The consequences of this include renal dysfunction hepatitis and stroke In this systematic review we aimed to evaluate the epidemiology clinical course and outcomes of patients who suffer from stroke as a complication of COVID 19 METHODS We conducted a systematic review of all studies published between November 1 2019 and July 8 2020 which reported on patients who suffered from stroke as a complication of COVID 19 RESULTS 326 studies were screened and 30 studies reporting findings from 55 176 patients including 899 with stroke were included The average age of patients who suffered from stroke as a complication of COVID 19 was 65 5 Range 40 4 76 4 years The average incidence of stroke as a complication of COVID 19 was 1 74 95 CI 1 09 to 2 51 The average mortality of stroke in COVID 19 patients was 31 76 95 CI 17 77 to 47 31 These patients also had deranged clinical parameters including deranged coagulation profiles liver function tests and full blood counts CONCLUSION Although stroke is an uncommon complication of COVID 19 when present it often results in significant morbidity and mortality In COVID 19 patients stroke was associated with older age comorbidities and severe illness PMID 33341565 PubMed as supplied by publisher