Related Articles Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan China PLoS One 2020 15 3 e0230548 Authors Yuan M Yin W Tao Z Tan W Hu Y Abstract Radiologic characteristics of 2019 novel coronavirus 2019 nCoV infected pneumonia NCIP which had not been fully understood are especially important for diagnosing and predicting prognosis We retrospective studied 27 consecutive patients who were confirmed NCIP the clinical characteristics and CT image findings were collected and the association of radiologic findings with mortality of patients was evaluated 27 patients included 12 men and 15 women with median age of 60 years IQR 47 69 17 patients discharged in recovered condition and 10 patients died in hospital The median age of mortality group was higher compared to survival group 68 IQR 63 73 vs 55 IQR 35 60 P 0 003 The comorbidity rate in mortality group was significantly higher than in survival group 80 vs 29 P 0 018 The predominant CT characteristics consisted of ground glass opacity 67 bilateral sides involved 86 both peripheral and central distribution 74 and lower zone involvement 96 The median CT score of mortality group was higher compared to survival group 30 IQR 7 13 vs 12 IQR 11 43 P 0 021 with more frequency of consolidation 40 vs 6 P 0 047 and air bronchogram 60 vs 12 P 0 025 An optimal cutoff value of a CT score of 24 5 had a sensitivity of 85 6 and a specificity of 84 5 for the prediction of mortality 2019 nCoV was more likely to infect elderly people with chronic comorbidities CT findings of NCIP were featured by predominant ground glass opacities mixed with consolidations mainly peripheral or combined peripheral and central distributions bilateral and lower lung zones being mostly involved A simple CT scoring method was capable to predict mortality PMID 32191764 PubMed indexed for MEDLINE