Mild traumatic brain injury mTBI has been linked to mental health disorders MHDs and pituitary function alterations. Due to the complex relationship of mTBI, the neuroendocrine system, and MHDs, we propose that neuroendocrine dysfunction NED may play a role in negative long term health outcomes. ...We hypothesized that NED either pre or post injury is associated with poor mental and physical health outcomes. Serum samples from the Armed Forces Health Surveillance Branch were obtained from concussed n 59 and non concussed n 72 SMs treated at the Concussion Restoration Care Center CRCC in Afghanistan. ...