The present study addresses this issue using data from the Canadian Study of Health and Aging CSHA , a prospective cohort of 10,263 subjects followed up from 1991 1992 through 2001 2002. ...Cox proportional hazards models were used to examine associations between aluminum and incident AD Hazard Ratios HRs , 95 confidence intervals CIs , adjusting for age, gender, history of stroke, education, and high blood pressure. ...