PrEP1519 is the first demonstration study in Latin America exploring acceptability use and persistence of pre exposure prophylaxis PrEP amongst adolescent men who have sex with men MSM and transgender women TGW aged 15 19 years The study is ongoing in three cities in Brazil Salvador S o Paulo and Belo Horizonte During the COVID 19 pandemic the PrEP1519 study team ensured a contingency plan to minimize effects of the pandemic disruptions on people participating in the study to initiate and continue accessing PrEP and other sexual health services They use telehealth platforms such as text messages online social media Instagram and Facebook and an artificial intelligence chatbot called Amanda Selfie to recruit participants provide peer support and care The team also provides discreet home delivery of condoms lubricants douches HIV self tests and medicines for PrEP In addition in person appointments remain possible when necessary Importance of maintaining HIV prevention services during the COVID 19 pandemicThe story of Miguel a young person who joined the study in July 2019 highlights the importance of maintaining HIV prevention services during the COVID 19 pandemic While Miguel was enrolled in the PrEP programme he reported poor adherence to his PrEP medication During the lockdown he contacted the PrEP1519 team for an HIV test due to an acute viral infection The test was facilitated under safe conditions at a PrEP1519 clinic He tested negative for HIV but positive for syphilis and was treated on the same day His partner however tested positive for HIV after which Miguel was tested again for HIV The second test confirmed that he was HIV negative Following his experience Pedro is motivated to continuing his PrEP regimen to prevent HIV Name changed for anonimity A PrEP1519 participant receives a home based HIV prevention kit during COVID 19 lockdown A member of the clinical team conducting a PrEP1519 telehealth consultationRapid test for syphilis at the PrEP1519 clinic The clinical team also advised that the participant s partner undergo STI and HIV testing PrEP1519 client with the physician prescribing PrEPAll photos credit Project PrEP1519