Related Articles Systemic steroids and risk of fecal oral shedding and increased transmission of SARS CoV 2 in pemphigus cases Clin Dermatol 2020 Nov Dec 38 6 750 756 Authors Pawar M Singh M Abstract Pemphigus and its variants viz vulgaris foliaceous vegetans Ig A pemphigus paraneoplastic pemphigus and Senear Usher syndrome are rare autoimmune blistering diseases of the skin and or mucous membranes The autoantibodies involved in the pathogenesis of pemphigus against desmoglein result in the breach of the skin and mucosal barrier which acts as the first line of defence against pathogens In this paper we underscore the importance of the integumentary system as a shield against the acquisition as well as transmission of SARS CoV 2 virion We have also made an attempt to delineate the various treatment modalities available and the viral drug dynamics involved in choosing the optimum therapeutic modality PMID 33341209 PubMed as supplied by publisher