Estrogen receptor ER silenced breast cancer cell lines exhibit endocrine resistance and morphological changes from an epithelial to a mesenchymal phenotype. ...AQP 1, 3, 4 and 5 expression localization was examined via reverse transcription quantitative PCR, western blotting and confocal microscopy in endocrine sensitive YS1.2 and resistant pII and MDA MB 231 breast cancer cells, as well as normal breast epithelial cells MCF10A . ...