Ebola virus infections lead to severe hemorrhagic fevers in humans and nonhuman primates and human fatality rates are as high as 67 90 . ...The absence of licensed vaccines and drugs against the Ebola virus impedes the prevention of viral infection. In this study, we generated recombinant baculoviruses rBV expressing the Sudan virus SUDV matrix structural protein VP40 rBV VP40 VP40 or the SUDV glycoprotein GP rBV GP GP , and SUDV virus like particles VLPs were produced by co infection of Sf9 cells with rBV SUDV VP40 and rBV SUDV GP. ...