Establishing a NBS in Morocco, is a challenging task due to multiple economic and social reasons, a specific screening in a Moroccan population using DMB urinary GAGs essay may allow for an earlier diagnosis of MPS. ...Screening of Imssouane children resulted in the detection of a 6 month old child, diagnosed with MPS I. CONCLUSIONS: Our results demonstrate the usefulness of quantifying glycosaminoglycans for early screening of MPS....