Objectives: Patients receiving long term anticoagulants were reported with varied health related quality of life HrQoL . We assessed HrQoL in patients receiving either warfarin or dabigatran from a tertiary care hospital.Methods: A cross sectional study was carried out following consent from patients on oral anticoagulants. ...Therapeutic PT INR and high medication adherence were the primary domains significantly associated with good quality of life amongst patients with warfarin.Conclusion: We observed good quality of life in patients receiving warfarin particularly those in the categories of elderly, with therapeutic PT INR and high medication adherence. ...