A series of 2 thio and 2 seleno acetamides bearing the benzenesulfonamide moiety were evaluated as Carbonic Anhydrase CA, EC 4.2.1.1 inhibitors against different pathogenic bacteria such as the Vibrio cholerae VchCA and VchCA , Burkholderia pseudomallei BpsCA and BpsCA , Mycobacterium tuberculosis Rv3723 and the Salmonella enterica serovar Typhimurium StCA2 . ...