Tuberculosis TB is a major health problem of global concern. The control of this disease requires appropriate preventive measures, including vaccines. ...Previous studies with Mycobacterium tuberculosis specific proteins have identified seven low molecular weight proteins, PE35, ESXA, ESXB, Rv2346c, Rv2347c, Rv3619c, and Rv3620c, as immunodominant antigens inducing Th1 cell responses in humans following natural infection with M. tuberculosis. ...