Although sickle cell disease is very common in Oman, priapism is a relatively rare complication of this disease. This study was aimed to identify the clinical and laboratory risk factors that predispose sickle cell disease patients to priapism. ...Patients with priapism were more likely to have acute chest syndrome, stroke, pulmonary hypertension, asplenia P 0.006 , gallbladder stones, and consequently cholecystectomy. ...